Morphokinetic Selection of Embryos (TIMELAPSE)
With the development and introduction of high assisted reproductive technologies infertile couples got an opportunity to have their own children. The possibilities of modern medicine bring hope to the hearts of people, even in such difficult situations, when it seems, there are no chances of success.
One of the latest achievements in this field is the embryo time-lapse technology during ivf process. The mother’s body securely protects embryos from the negative impact of external factors, providing them with stable conditions of growth and development. Being outside of the human body during ivf process, they are extremely sensitive to changes in the cultivation conditions. Under the laboratory conditions to assess the quality and speed of embryo development, to select embryos for transfer, cryopreservation embryologist should examine them with a microscope at regular intervals. Naturally, this standard procedure for all the embryology laboratories takes place outside the incubator. A number of important parameters of the culture medium, where the embryos are located, are changing. In addition to it the embryos are also exposed to light and electromagnetic fields during the examination. These effects have a negative impact on the pace and quality of the embryo growth during ivf process.
To exclude the effects of negative factors the «Father, Mother and Baby» medical center introduced the time-lapse technology of imaging embryos. This system makes it possible to estimate the rate of growth and development of embryos with minimal external influence. The system takes photos of each embryo with a predetermined frequency during the entire period of cultivation. The light effect on the embryo during this is reduced to 90% compared with the standard inspection under a microscope.
But the main advantage of the technology is that during the cultivation by ivf process of several embryos time-lapse allows you to get the most detailed chronology of the development and, on the basis of these data, to choose embryos for transfer with the highest potential for implantation, respectively, increasing the chance of pregnancy. In the standard protocol of cultivation and evaluation of morphological characters an embryologist can hold 2 to 4 examinations (photoshots). The use of technology provides a new approach to the selection of embryos and increases pregnancy rates.